منابع مشابه
Unresponsiveness to Recombinant Hepatitis B Vaccine in Healthy Iranian Neonates: Association with HLA Antigens
Background: Hepatitis B is an important infectious disease. Since several years ago, mass vaccination against this viral infection has become as part of routine vaccination schedule of Iran. However, some healthy neonates, children and adults fail to generate a protective antibody response after vaccination.Objectives: To investigate distribution of HLA class-I and class-II antigens in health...
متن کاملExpression of S and pre s2 Hepatitis B Surface Antigens in Mammalian Cos-7 Cell Line
Hepatitis B virus (HBV) is a serious global health problem. The development of a safe and effective vaccinewould help infection prevention. Previous hepatitis B vaccine production involved the isolation of the noninfectious particle from chronic HBV carriers. DNA recombinant technology has been used for vaccineproduction without having been contaminated with blood-born infectious ag...
متن کاملHepatitis B antigens in serum and liver of chimpanzees acutely infected with hepatitis B virus.
We report the temporal patterns of various immunohistological and serological parameters of acute self-limited hepatitis B virus infection of two chimpanzees, and we provide evidence that the synthesis of hepatitis B core antigen precedes that of hepatitis B surface antigen. Our data suggest that existence of a biphasic hepatitis B virus infection involving a hematogenous reinfection of the liv...
متن کاملHepatitis B Virus Core-related Antigens as a Marker for Monitoring of Chronic Hepatitis B Infection
*Correspondence and reprint request: Dr. Man-Fung Yuen, Department of Medicine, The University of Hong Kong Queen Mary Hospital, Pokfulam Road, Hong Kong SAR, China. Tel: (852) 28553984 Fax: (852) 28725828 E-mail: [email protected] AC CE PT ED Copyright © 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. J. Clin. Microbiol. doi:10.1128/JCM.00...
متن کاملHepatitis B virus core-related antigens as markers for monitoring chronic hepatitis B infection.
A sensitive chemiluminescence enzyme immunoassay has been developed for hepatitis B virus (HBV) core-related antigen (HBcrAg) detection. We aimed to investigate the usefulness of HBcrAg measurement for monitoring chronic hepatitis B disease. HBcrAg levels were measured by a chemiluminescence enzyme immunoassay in 54 untreated patients and 39 patients treated with either entecavir or lamivudine....
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ژورنال
عنوان ژورنال: Nature
سال: 1975
ISSN: 0028-0836,1476-4687
DOI: 10.1038/253013a0